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Related Experiment Videos

Corrected seminal fructose test

G F Gonzales1

  • 1Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima.

Archives of Andrology
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Leukocytospermia, characterized by white blood cells in semen, may indicate reproductive tract obstruction. Combined tests of normal serum testosterone and low corrected seminal fructose levels can help identify this obstruction.

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Area of Science:

  • Reproductive Endocrinology
  • Andrology
  • Clinical Chemistry

Background:

  • Infertility affects a significant portion of the male population.
  • Inflammation within the reproductive tract can lead to male infertility.
  • Identifying obstructive processes is crucial for diagnosing and treating male infertility.

Purpose of the Study:

  • To evaluate the combined use of serum testosterone and corrected seminal fructose levels as a diagnostic marker for obstructive processes in the male reproductive tract.
  • To investigate the relationship between seminal leukocytes, corrected seminal fructose, and serum testosterone levels in infertile men.

Main Methods:

  • Serum testosterone, seminal fructose, citric acid, and prolactin were measured in 33 infertile men.
  • Seminal samples were analyzed for leukocytes using the peroxidase stain technique.

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  • Corrected seminal fructose was calculated from actual fructose concentration.
  • Subjects were categorized into groups with and without leukocytospermia.

    • Main Results:

    • Seminal fructose and corrected fructose were significantly lower in men with leukocytospermia.
    • Serum testosterone, seminal prolactin, and citric acid levels did not differ between groups.
    • In 61.5% of leukocytospermic samples, low corrected seminal fructose and normal serum testosterone were observed, suggesting obstruction.
    • Seminal prolactin levels in leukocytospermic subjects correlated more with citric acid than corrected fructose, indicating potential prostatic secretion.

    Conclusions:

    • The combination of leukocytospermia, normal serum testosterone, and low corrected seminal fructose levels suggests a possible obstructive process in the seminal vesicles.
    • This diagnostic approach may aid in identifying inflammatory obstruction in the male reproductive tract.
    • Further research is warranted to confirm the utility of these markers in clinical practice.