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Updated: Jul 28, 2026
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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Total knee arthroplasty in Parkinson's disease
A Fast1, E Mendelsohn, J Sosner
1Department of Physical Medicine and Rehabilitation, St. Vincent's Hospital and Medical Center of New York, NY 10011.
Archives of Physical Medicine and Rehabilitation
|November 1, 1994
Summary
Total knee replacement may be suitable for Parkinson's disease (PD) patients who can walk and follow commands. Rehabilitation may be longer for PD patients, highlighting the need for pre-surgical studies.
Area of Science:
- Orthopedic Surgery
- Neurology
Background:
- Parkinson's disease (PD) is rarely considered for total knee arthroplasty (TKA).
- Some literature suggests PD is a contraindication for TKA.
Observation:
- A case study of a 77-year-old male with PD undergoing TKA for severe degenerative joint disease.
- The patient experienced a prolonged but successful inpatient rehabilitation and continued improvement post-discharge.
Findings:
- The patient achieved independent functional ambulation post-TKA.
- Patients with PD maintaining ambulatory function and cognitive ability may be candidates for TKA.
- Rehabilitation can be significantly prolonged and more challenging in PD patients, even with mild symptoms.
Implications:
- Recommends considering TKA for indicated PD patients with preserved function and cognition.
- Highlights the need for objective studies on pre-surgical rehabilitation for PD patients undergoing TKA.
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