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The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
Published on: February 3, 2012
[Placentitis induced by hepatitis viruses]
The results of morphological studies of 66 placentas from women suffering from various forms of viral hepatitis and HBs antigen carriers as well as results of a pathomorphological study of a late abortion, 3 stillborns and 2 newborns are presented. 33 placentas showed lymphocytic infiltration of varying degree and vasculitis. Of most importance were cellular changes, particularly in the decidua, with the appearance in the nuclei of inclusions similar to those found in the liver affected with viral hepatitis. A correlation is observed in some cases between liver changes in the mother, placental alterations and changes in the child.
The results of morphological studies of 66 placentas from women suffering from various forms of viral hepatitis and HBs antigen carriers as well as results of a pathomorphological study of a late abortion, 3 stillborns and 2 newborns are presented. 33 placentas showed lymphocytic infiltration of varying degree and vasculitis. Of most importance were cellular changes, particularly in the decidua, with the appearance in the nuclei of inclusions similar to those found in the liver affected with viral hepatitis. A correlation is observed in some cases between liver changes in the mother, placental alterations and changes in the child.
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