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Updated: Aug 15, 2026

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
Published on: May 11, 2016
[The structural and metabolic characteristics of squamous-cell cancer of the larynx]
Abstract:
A quantitative histochemical study of 50 cases of laryngeal squamous-cell carcinoma established differences in the structural-metabolic indices characterized by tumour growth and differentiation. Tumor epithelium exhibited lower activity of the aerobic oxidation enzymes and by a lower content of the nuclear nucleic acids. Differentiation of multilayer epithelium of laryngeal mucous membrane in followed by an increase of the histochemical index dispersion. The dispersion of the structural-metabolic indices is decreasing in the tumor epithelium in the process of differentiation and keratinization. The highest degree of anaplasia is observed in the keratinizing form of carcinoma.
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