Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Occult subacute thyroiditis mimicking classic giant cell arteritis

E D Rosenstein¹, N Kramer

¹Arthritis and Rheumatic Disease Center, West Orange, NJ 07052.

Arthritis and Rheumatism

|November 1, 1994

Summary

Subacute thyroiditis can mimic giant cell arteritis (GCA) symptoms like fever and pain. Early diagnosis and appropriate treatment, not just GCA management, are crucial for patient recovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Restorative interventions and management of primary and permanent molars affected by molar incisor hypo-mineralization: a systematic review.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2026

Same author

Hypersensitivity associated with molar-incisor hypomineralisation (MIH) among elementary schoolchildren in Bavaria, Germany: results from a cross-sectional study.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2025

Same author

Interdisciplinary management of patients with special healthcare needs undergoing dental treatment in a tertiary care hospital setting in Germany: a retrospective study.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2025

Same author

Hypomineralised second primary molars: the Würzburg concept.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2024

Same author

Clinical effectiveness of pit and fissure sealants in primary and permanent teeth of children and adolescents: an umbrella review.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2024

Same author

Checkpoint inhibitor-induced bullous pemphigoid differs from spontaneous bullous pemphigoid.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024

Area of Science:

Endocrinology
Rheumatology
Internal Medicine

Background:

Giant cell arteritis (GCA) is a vasculitis often presenting with constitutional symptoms and elevated inflammatory markers.
Prompt diagnosis and treatment of GCA are essential to prevent complications such as vision loss.

Observation:

A 60-year-old man presented with symptoms suggestive of GCA, including fever, weight loss, aching, and a high erythrocyte sedimentation rate (125 mm/hour).
Initial treatment with prednisone for presumed GCA led to symptom improvement, but temporal artery biopsy was unremarkable.
Thyroid function tests revealed hyperthyroidism (elevated T4, suppressed TSH) and suppressed radioactive iodine uptake.

Findings:

The patient was diagnosed with subacute thyroiditis, a condition that can present with constitutional symptoms overlapping with GCA.

Related Experiment Videos

Treatment was shifted from high-dose prednisone to beta-blockers after tapering steroids.

The patient recovered and normalized thyroid function without recurrence of symptoms.

Implications:

This case highlights the importance of considering subacute thyroiditis in the differential diagnosis of suspected GCA, especially when clinical or biopsy findings are atypical for GCA.
Misdiagnosis can lead to prolonged or unnecessary corticosteroid treatment.
Comprehensive evaluation is key to differentiate between these conditions and ensure appropriate management.