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Related Experiment Videos

Pseudohyperphosphataemia incidence in an automatic analyzer

A M Cohen1, A Magazanik, E van-der Lijn

  • 1Hamatology Unit, Hasharon Hospital, Golda Medical Center, Petah-Tikva, Israel.

European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies
|July 1, 1994
PubMed
Summary
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High globulin levels in multiple myeloma patients can cause falsely elevated phosphate readings on the Hitachi 717 analyser. This pseudohyperphosphataemia occurs due to interference with the ammonium molybdate method.

Area of Science:

  • Clinical Chemistry
  • Hematology
  • Analytical Biochemistry

Background:

  • Multiple myeloma is associated with hyperglobulinaemia.
  • Routine blood analysis may yield inaccurate inorganic phosphate levels in certain patient populations.
  • The Hitachi 717 analyser utilizes an ammonium molybdate method for phosphate determination.