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Mantel-Haenszel-type tests for testing equivalence or more than equivalence in comparative clinical trials
T Yanagawa1, T Tango, Y Hiejima
1Department of Mathematics, Kyushu University, Fukuoka, Japan.
Biometrics
|September 1, 1994
Abstract:
This paper proposes Mantel-Haenszel-type statistics for testing whether a new treatment is at least as effective as the standard treatment in comparative binomial trials. The null hypotheses considered are of a specified nonzero difference and of a ratio not equal to unity. It is shown that we may also use these tests for testing the equivalence of two treatments.