Nitric oxide controls feeding behavior in the chicken
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Updated: Nov 11, 2026

Combining Quantitative Food-intake Assays and Forcibly Activating Neurons to Study Appetite in Drosophila
Published on: April 24, 2018
Y H Choi1, M Furuse, J Okumura
1Laboratory of Animal Nutrition, School of Agriculture, Nagoya University, Japan.
Abstract:
To investigate the effect of nitric oxide (NO) on food intake in the chicken, L-NG-nitro-arginine methyl ester HCl (L-NNA), an inhibitor of NO synthase, was applied. When i.p. administered, L-NNA significantly inhibited the food intake of broiler chickens in a dose response manner. Food ingestion was also depressed by the i.c.v. injection of L-NNA in a dose response fashion. The effect of L-NNA was attenuated by i.c.v. administration of L-arginine. These results suggest that central NO may control feeding behavior in the chicken.
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