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Published on: December 28, 2021
Prostaglandin E1 as treatment for erectile failure in elderly men
M F Godschalk1, J Chen, P G Katz
1Division of Geriatrics, Medical College of Virginia, Richmond.
Objective:
To determine the efficacy of intracavernosal injection of prostaglandin E1 (alprostadil) in elderly men with erectile failure.
Design:
Prospective study.
Setting:
Outpatients at a university-affiliated VA Medical Center.
Participants:
Ten subjects aged 65 years and older with duration of erectile failure of 6 months or longer.
Interventions:
Subjects received intracavernosal injections of prostaglandin E1 in the office and self-administered intracavernosal prostaglandin E1 at home.
Measurements:
Penile rigidity was measured by palpation and by the Rigiscan rigidity monitor.
Results:
Intracavernosal injection of prostaglandin E1 produced erections adequate for intercourse in 9 of the 10 subjects. Attempts at intercourse were rated satisfactory by two-thirds of the subjects and their spouses.
Conclusions:
Intracavernosal injection of prostaglandin E1 is safe and effective for erectile failure in elderly men.
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