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Congo red prolongs the incubation period in scrapie-infected hamsters
L Ingrosso1, A Ladogana, M Pocchiari
1Laboratory of Virology, Istituto Superiore di Sanità, Rome, Italy.
Journal of Virology
|January 1, 1995
Abstract:
In scrapie-infected cells, Congo red inhibits both the replication of the infectious agent and accumulation of the protease-resistant form of PrP (PrP-res). In this report, we show that Congo red prolongs the incubation periods of hamsters experimentally infected with two different strains of scrapie.