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[Bacterial endotoxins: a pathogenic factor in asthma?]
1Clinique de Pneumologie, Hôpital Saint-Pierre, Bruxelles.
Abstract:
Though the house dust mite allergen is considered as one of the most important factors in perennial asthma, several observations suggest that it could be but one of several factors leading to asthma. Exposure to bacterial endotoxins has been associated with some occupational chronic obstructive bronchial diseases. In the present work, endotoxins were measured in the house dust, and observations of the skin and bronchial challenge tests as well epidemiological studies suggest that they play a role in asthma.
Insights
Bacterial endotoxins in house dust may contribute to asthma development, alongside house dust mite allergens. Studies indicate endotoxins play a role in asthma, suggesting multiple factors are involved.
Area of Science:
- Environmental Health
- Immunology
- Respiratory Medicine