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Disorders of the central nervous system
1Department of Obstetrics and Gynecology, Tufts University School of Medicine, Boston, MA 02111.
Seminars in Perinatology
|August 1, 1994
Summary
This review covers common fetal central nervous system (CNS) abnormalities, including ventriculomegaly, Dandy-Walker malformation (DWM), holoprosencephaly, anencephaly, and spina bifida. Prognosis varies based on associated anomalies and defect characteristics.
Area of Science:
- Perinatal Medicine
- Neuroscience
- Developmental Biology
Background:
- Central nervous system (CNS) abnormalities are significant concerns in perinatal medicine.
- Early identification and understanding of these conditions are crucial for management and prognosis.
Purpose of the Study:
- To review common CNS abnormalities encountered in perinatal medicine.
- To discuss diagnostic aids and prognostic factors for these conditions.
Main Methods:
- Literature review of common CNS abnormalities in perinatal medicine.
- Discussion of diagnostic features and treatment approaches.
Main Results:
- Prognosis of ventriculomegaly correlates with associated anomalies.
- Dandy-Walker malformation (DWM) treatment involves shunting.
- Facial features aid in diagnosing holoprosencephaly.
- Anencephaly is a lethal anomaly.
- Spina bifida outcomes depend on defect characteristics and associated anomalies.
Conclusions:
- Accurate diagnosis of CNS abnormalities in the perinatal period is essential.
- Prognostic indicators vary among different CNS malformations.
- Management strategies are condition-specific.