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Excel: a new frontier in haemapheresis

A Zanella1

  • 1DIDECO S.p.A., Mirandola, Italy.

Annales De Medecine Interne
|January 1, 1994
PubMed
Summary

The Dideco Excel cell separator enhances haemapheresis with improved performance and safety. This innovative device offers higher platelet yield and purity while reducing procedure time and donor discomfort.

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Area of Science:

  • Blood science
  • Medical technology
  • Biomedical engineering

Background:

  • Haemapheresis is evolving with increased demand for stem cells and single donor platelets.
  • Existing cell separators require advancements for higher performance, yield, and user safety.

Purpose of the Study:

  • To introduce the Dideco Excel, an innovative automatic blood cell separator.
  • To highlight its technological features and their impact on haemapheresis.

Main Methods:

  • Utilizes a charged coupled device (CCD) for automatic buffy coat control.
  • Features a double eccentric-plate separation chamber and a multi-processor system.
  • Incorporates a touch screen interface and load cell transducers for fluid balancing.

Main Results:

  • Achieves high platelet yield (> 5 x 10^11 PLT) with low white blood cell contamination (< 5 x 10^6 WBC).
  • Reduces procedure time to 60 minutes for one platelet unit and 120 minutes for two.
  • Enhances product quality with lower platelet and complement activation, and reduced anticoagulant citrate dextrose (ACD) consumption.

Conclusions:

  • The Dideco Excel represents a new generation of cell separators for haemapheresis.
  • Its advanced technology offers superior performance, safety, and user-friendliness.
  • Sets new standards in the field of automated blood cell separation.

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