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[Recent proposals for early stage clinical trials of cancer]
1Dept. of Biostatistics and Epidemiology, School of Health Sciences and Nursing, University of Tokyo.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|October 1, 1994
Abstract:
Statistical designs for early stage cancer clinical trials, which include continual reassessment method for phase I and I-II studies, early stopping of phase II studies, randomized phase II and multi-stage phase II studies, are shortly reviewed. These recent proposals should be examined further as regards to their statistical characteristics as well as their ethical implication.