Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interocular transfer in the split-brain rat

D P Crowne1, P Forsyth, J Fitzgerald

  • 1Department of Psychology, University of Waterloo, Ontario, Canada.

Behavioral Neuroscience
|August 1, 1994
PubMed
Summary

Interocular transfer of visual learning in rats relies on the corpus callosum. Severing this pathway disrupts the brain

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Image quality assessment in mammography of women with cardiac implantable electronic devices: An insight into radiographers' experiences in Australia.

Radiography (London, England : 1995)·2026
Same author

Virtual Nursing in Residential Aged Care: What Is Known? A Rapid Review.

Journal of advanced nursing·2025
Same author

Australian radiographers' approaches to mammographic imaging of women with cardiac implantable electronic devices.

Radiography (London, England : 1995)·2025
Same author

Large-scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 children and adolescents.

Human brain mapping·2024
Same author

Cost-effectiveness analysis of health tapestry, a complex primary care program for older adults: a post-hoc analysis.

BMC primary care·2024
Same author

Attenuated psychosis symptoms are related to working alliance between therapist and service user.

Early intervention in psychiatry·2024

Area of Science:

  • Neuroscience
  • Comparative Psychology

Background:

  • Interocular transfer (IOT) demonstrates visual information sharing between brain hemispheres.
  • The optic chiasm transection method in rats allows for studying IOT in split-chiasm preparations.
  • The corpus callosum's role in interhemispheric communication is crucial for IOT.

Purpose of the Study:

  • To investigate the role of the corpus callosum in interocular transfer of visual learning.
  • To compare IOT in split-chiasm rats with intact versus sectioned corpus callosum.

Main Methods:

  • Rats with transected optic chiasms underwent monocular training on an orientation discrimination task.
  • Training was alternated between eyes, with subsequent retraining or reversal tasks.
  • Interocular transfer was assessed by savings in relearning or retraining.

Main Results:

  • Split-chiasm rats with intact corpus callosum showed significant savings (55%) for the correct stimulus (S+) when transferred to the first eye.
  • Savings were not observed for the incorrect stimulus (S-).
  • Split-brain rats (callosum sectioned) showed disrupted transfer, requiring original learning levels for retraining with the second eye's stimulus.

Conclusions:

  • The corpus callosum is essential for effective interocular transfer of visual learning in rats.
  • Callosal sectioning significantly impairs or abolishes interocular transfer, supporting its role in interhemispheric communication.
  • Findings align with previous studies in cats and monkeys regarding callosal function in IOT.

Related Experiment Videos