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Epstein-Barr virus associated posttransplant malignant lymphoma in renal allograft recipients

Y J Choi1, C S Kang, W S Shin

  • 1Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea.

We report two cases of posttransplant malignant lymphoma(PTML) of B cell origin associated with Epstein-Barr virus(EBV) infection. They were a 52-year-old male and a 37 year-old-female, in whom intermediate-grade diffuse malignant lymphomas of large cell type developed in the submandibular area and jejunum, respectively. DNA and RNA in situ hybridization revealed the presence of EBV-specific DNA and RNA sequences in the tumor cells.

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