[Correlation and allergenicity of industrial substances and their chemical structure]

Allergic effects of 575 various chemicals were studied. 20.9% of the chemicals were industrial allergens, 13.6%--mild sensitizers, and 65.5% of substances had no such effects. Allergic properties appeared to depend not on so-called "allergenic" groups, but on interaction between active radicals and all structures of molecule. Sensitization in this case occurs mainly due to properties of the main structure determining common features of all chemical class, secondary elements of the molecule conditioned the intensity of specific effects.