[The metastatic pattern of malignant tumors]

Area of Science:

• Oncology
• Pathology

Context:

• Analysis of 400 autopsy cases reveals patterns of malignant tumor metastasis.
• Carcinomas comprised 80.3% and sarcomas 19.7% of malignant tumors.

Purpose:

• To investigate the common sites and origins of tumor metastasis in autopsy cases.
• To identify factors influencing the patterns of malignant tumor spread.

Summary:

• Lung and liver metastasis were frequent (40.5%), with common primary sites including breast, gastrointestinal tract, ovary, and non-Hodgkin lymphoma (NHL).
• Lymph node metastasis occurred primarily in the neck, mediastinum, and aorta.
• While lung, gastric, breast, and NHL showed extensive metastasis, cervical, bladder, pharyngeal, and testicular carcinomas predominantly showed local infiltration.
• Tumor metastasis patterns are influenced by anatomical region, histologic type, and differentiation.

Impact:

• Provides insights into metastatic patterns of various malignant tumors.
• Highlights the importance of primary tumor characteristics in predicting metastatic spread.
• Informs clinical strategies for monitoring and managing cancer metastasis.