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Related Experiment Videos

Mechanical ventilators optimized for pediatric use decrease work of breathing and oxygen consumption during

M F el-Khatib1, R L Chatburn, D L Potts

  • 1Division of Pediatric Pharmacology, Rainbow Babies and Childrens Hospital, Cleveland, OH 44106.

Critical Care Medicine
|December 1, 1994
PubMed
Summary
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The Bird VIP ventilator significantly reduced work of breathing and oxygen consumption (VO2) in pediatric patients compared to other models. Changes in VO2 may help track work of breathing, potentially aiding in ventilator weaning.

Area of Science:

  • Pediatric critical care medicine
  • Respiratory physiology
  • Mechanical ventilation

Background:

  • Assessing patient work of breathing is crucial for optimizing mechanical ventilation in pediatric patients.
  • Different ventilators may impact the effort required for a patient to trigger a breath during pressure-support ventilation.
  • Oxygen consumption (VO2) is a physiological parameter that may correlate with the energy expenditure of breathing.

Purpose of the Study:

  • To evaluate if different ventilators affect the work of breathing in pediatric patients on pressure-support ventilation.
  • To determine if changes in oxygen consumption (VO2) correlate with changes in work of breathing.

Main Methods:

  • Prospective study conducted in a university hospital's pediatric intensive care unit.

Related Experiment Videos

  • Nine mechanically ventilated pediatric patients (2-75 months) were studied.
  • Patients received pressure-support ventilation from three different ventilators (Siemens Servo 900C, Bird VIP, Newport Wave E200) in random order.

    • Main Results:

    • The Bird VIP ventilator resulted in significantly lower work of breathing and oxygen consumption (VO2) compared to the Siemens Servo 900C and Newport Wave E200.
    • The Newport Wave E200 also showed significantly lower work of breathing and VO2 than the Siemens Servo 900C.
    • Trends in VO2 closely mirrored trends in work of breathing across all ventilators, with no significant changes in patient distress scores.

    Conclusions:

    • Modern mechanical ventilators, particularly the Bird VIP, can significantly reduce work of breathing and VO2 in pediatric patients.
    • The Bird VIP's ability to lower work of breathing and VO2 suggests better patient-ventilator synchrony and potential for facilitating ventilator weaning.
    • Monitoring changes in VO2 may serve as a useful surrogate for tracking changes in work of breathing.