Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

General principles of surgery quality control

E C Holmes1

  • 1Department of Surgery/Oncology, University of California at Los Angeles.

Chest
|December 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reagent contamination in viromics: all that glitters is not gold.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2019
Same author

Experimental Verification of Seed Transmission of Zucchini yellow mosaic virus.

Plant disease·2019
Same author

Transgenic Virus Resistance in Crop-Wild Cucurbita pepo Does Not Prevent Vertical Transmission of Zucchini yellow mosaic virus.

Plant disease·2019
Same author

Establishment and cryptic transmission of Zika virus in Brazil and the Americas.

Nature·2017
Same author

Phylogenetic Diversity of Koala Retrovirus within a Wild Koala Population.

Journal of virology·2016
Same author

Analysis of viral (zucchini yellow mosaic virus) genetic diversity during systemic movement through a Cucurbita pepo vine.

Virus research·2014

High-quality randomized clinical trials require robust infrastructure, including skilled personnel and standardized procedures. Rigorous quality control and statistical monitoring are crucial for reliable treatment data generation.

Area of Science:

  • Clinical Research Methodology
  • Evidence-Based Medicine
  • Surgical Trials

Background:

  • Randomized clinical trials (RCTs) are the gold standard for generating reliable treatment data.
  • Ensuring the quality and statistical credibility of RCTs is paramount for valid outcomes.
  • Effective RCTs necessitate a multidisciplinary approach involving various healthcare professionals.

Purpose of the Study:

  • To outline essential components for conducting high-quality randomized clinical trials.
  • To emphasize the critical role of infrastructure, personnel, and procedural standardization in RCTs.
  • To highlight key considerations for surgical trials, particularly in phase 3 studies.

Main Methods:

  • The abstract emphasizes the necessity of a well-structured operating infrastructure.

Related Experiment Videos

  • It highlights the importance of nurse data managers, coordinators, statisticians, surgeons, and physicians.
  • Key procedural elements include intraoperative staging, surgical standardization, and strict eligibility criteria enforcement.

    • Main Results:

    • The abstract does not present empirical results but rather outlines methodological requirements.
    • It stresses the need for careful stratification based on prognostic variables before randomization in phase 3 trials.
    • Successful implementation of these methods ensures the integrity and reliability of trial data.

    Conclusions:

    • High-quality randomized clinical trials depend on meticulous planning and execution.
    • Robust infrastructure, skilled multidisciplinary teams, and standardized procedures are indispensable.
    • Adherence to strict criteria and pre-randomization stratification is vital for generating credible treatment data.