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The human RAD51/RecA homologue gene is not a candidate gene for Bloom's syndrome
D Hellgren1, S Sahlén, S Ljungqvist
1Unit for Environmental Medicine, Karolinska Institute, NOVUM, Huddinge, Sweden.
Human Genetics
|December 1, 1994
Abstract:
The human gene HSRAD51/RecA homologue has been investigated as a possible candidate gene involved in Bloom's syndrome. No mutations were found in the cDNA isolated from three different Bloom's syndrome cell lines, thus excluding the possibility that HSRAD51 is directly involved in the syndrome. Other possible candidates are discussed.