Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Resorption patterns following intentional vital root transection in Macaca mulatta

R Allen1, P L Sadowsky, C F Cox

  • 1Department of Orthodontics, School of Dentistry, University of Alabama, Birmingham.

The International Journal of Adult Orthodontics and Orthognathic Surgery
|January 1, 1994
PubMed
Summary

This study on Macaca mulatta found severe bone resorption initially after vital root transection, which decreased over 52 weeks. New cementum formation occurred along the cut surface and within the pulp canal.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antimicrobial Stewardship in German non-university hospitals: baseline status and impact of a multifaceted AMS intervention within the prospective ID ROLL OUT study.

Infection·2025
Same author

Steatotic liver disease is a marker of multimorbidity, not underlying cirrhosis, in older adults.

Npj gut and liver·2025
Same author

Phase transitions in random circuit sampling.

Nature·2024
Same author

Phase and amplitude responses for delay equations using harmonic balance.

Physical review. E·2024
Same author

Dynamics of magnetization at infinite temperature in a Heisenberg spin chain.

Science (New York, N.Y.)·2024
Same author

Insights into oscillator network dynamics using a phase-isostable framework.

Chaos (Woodbury, N.Y.)·2024

Area of Science:

  • Oral surgery
  • Periodontology
  • Histopathology

Background:

  • Previous research documented nerve and periodontal tissue changes after vital root transection in Macaca mulatta.
  • The effects of this surgery on tooth root and supporting bone structures remained largely unexamined.

Purpose of the Study:

  • To histopathologically evaluate bone and root structure changes over a 1-year period following vital root transection.

Main Methods:

  • Vital root transection was performed on the apical one third of teeth in three adult Macaca mulatta.
  • Surgically closed sites were maintained on a soft diet for 7 days, followed by normal mastication.
  • Tissue samples were collected at 1, 2, 3, 6, 24, and 52 weeks, then demineralized, sectioned, and stained for microscopic evaluation of resorption.

Related Experiment Videos

Main Results:

  • Severe bone resorption was observed at 1 week, diminishing progressively up to 52 weeks.
  • Active inflammatory root resorption was most prominent in premolars and molars at 1 week, with arrested resorption noted by week 3.
  • New cementum formation was evident on the cut root surface from 2 to 52 weeks and within the pulp canal starting at 2 weeks.

Conclusions:

  • Vital root transection in Macaca mulatta leads to significant initial bone and root resorption.
  • The process of resorption appears to arrest over time, with new cementum formation indicating healing.
  • Findings provide insights into the long-term tissue response following this surgical procedure.