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Published on: May 15, 2020
Salvage of clotted jugular vein hemodialysis catheters
D Shrivastava1, A P Lundin, B Dosunmu
1Renal Division, Interfaith Medical Center, Brooklyn, N.Y.
Insights
Clotted jugular venous catheters (JVC) can be reopened using a guide wire technique when urokinase fails. This method successfully restored hemodialysis access in 87.5% of patients, salvaging most catheters.
Area of Science:
- Nephrology
- Vascular Access Management
- Interventional Procedures
Background:
- Jugular venous catheters (JVC) are crucial for hemodialysis in acute and end-stage renal disease.
- Catheter clotting and occlusion frequently necessitate alternative vascular access.
- Urokinase is effective for declotting but has high recurrence rates.
Purpose of the Study:
- To evaluate the efficacy of a guide wire insertion technique for salvaging occluded JVCs.
- To determine if guide wire insertion can restore patency in JVCs unresponsive to urokinase.
- To assess the impact of this technique on facilitating continued hemodialysis.
Main Methods:
- A cohort of 24 patients with clotted JVCs (occlusion within 6-55 days) was studied.
- Urokinase infusion (5,000 IU) into both catheter lumens was initially unsuccessful.
- A soft-tipped guide wire was inserted into both arterial and venous lumens of the occluded JVCs.
Main Results:
- Guide wire insertion successfully opened occluded JVCs in 21 out of 24 patients (87.5%).
- Immediate initiation of hemodialysis was possible in salvaged catheters.
- The technique proved effective for JVCs unresponsive to urokinase therapy.
Conclusions:
- Guide wire insertion is a highly effective method for salvaging urokinase-refractory occluded JVCs.
- This technique facilitates continued hemodialysis by restoring catheter patency.
- It offers a valuable alternative to replacing occluded JVCs, improving patient management.
Abstract:
Jugular venous catheters (JVC) provide rapid, vascular access for both emergency and maintenance hemodialysis in both acute and end-stage renal disease. Clotting and occlusion of JVC is a common problem necessitating alternate vascular access. Urokinase will declot 80-90% of central venous catheters; however, recurrence of catheter occlusion is frequent. We successfully employed a guide wire insertion technique to salvage occluded JVC after failed urokinase infusion. In 24 patients JVCs, inserted for either temporary or permanent vascular access, clotted within 6-55 days of initiating hemodialysis. Urokinase (5,000 IU) instilled into both arterial and venous limbs of the catheter had been unsuccessful in restoring patency. In these patients, we inserted a soft-tipped guide wire into both lumina. In 21 of 24 patients (87.5%), guide wire insertion opened the occluded JVC, permitting immediate initiation of hemodialysis. We conclude that for clotted JVC unresponsive to urokinase infusion, guide wire insertion can salvage most catheters thereby facilitating hemodialysis.
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