Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brain atriopeptin mediates AV3V depressor response

Y H Ku1, T Zhang

  • 1Department of Physiology, Beijing Medical University, China.

Peptides
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mathematical model of biofilm induced calcite precipitation.

Water science and technology : a journal of the International Association on Water Pollution Research·2010
Same author

Origins of endomorphin-2 immunopositive fibers and terminals in the spinal dorsal horn of the rat.

Neuroscience·2010
Same author

Development of in vitro culture method for early stage zebrafish (Danio rerio) ovarian follicles for use in cryopreservation studies.

Theriogenology·2010
Same author

Post weaning social isolation influences spatial cognition, prefrontal cortical synaptic plasticity and hippocampal potassium ion channels in Wistar rats.

Neuroscience·2010
Same author

Molecular epidemiological survey of haemoglobinopathies in the Guangxi Zhuang Autonomous Region of southern China.

Clinical genetics·2010
Same author

YKL-40 in asthmatic patients, and its correlations with exacerbation, eosinophils and immunoglobulin E.

The European respiratory journal·2010
Same journal

Potential role of intelectin-1 in the regulation of feeding of goldfish (Carassius auratus).

Peptides·2026
Same journal

Cocaine- and amphetamine-regulated transcript (CART) peptides: Neuroanatomical distribution and functional implications in the mammalian central nervous system.

Peptides·2026
Same journal

P1642-1, a novel pancreatic polypeptide analogue, ameliorates cognitive impairment in 5 ×FAD mice and is associated with enhanced PINK1/Parkin-related mitophagy.

Peptides·2026
Same journal

Structure-based rational design of high-affinity JAZF1 variants peptides to target the testicular orphan nuclear receptor 4 and pro-opiomelanocortin axis in Cushing's disease.

Peptides·2026
Same journal

[Gly<sup>2</sup>]-GLP-2(1-5): An ultra-short GLP-2 peptide for intestinal mucosal protection in inflammatory bowel disease.

Peptides·2026
Same journal

The role of Kiss1 neurons in regulating metabolism and energy balance.

Peptides·2026
See all related articles

Sodium L-glutamate injection into the AV3V region of rats causes a drop in blood pressure. Atriopeptin in the nucleus paraventricularis and cardiac vagus nerve excitation mediate this depressor response.

Area of Science:

  • Neuroscience
  • Cardiovascular Physiology

Background:

  • The anteroventral third ventricle (AV3V) region plays a role in cardiovascular regulation.
  • The involvement of specific neurochemicals and pathways in AV3V-mediated cardiovascular responses requires further elucidation.

Purpose of the Study:

  • To investigate the role of sodium L-glutamate (Glu) in the AV3V region on cardiovascular parameters.
  • To identify the neurochemical mediators and neural pathways involved in the AV3V-induced depressor response.

Main Methods:

  • Microinjections of sodium L-glutamate into the AV3V region of urethane-anesthetized rats.
  • Administration of procaine, atriopeptin III antiserum, methyl atropine, phentolamine, and propranolol to assess their effects on the depressor response.

Main Results:

Related Experiment Videos

  • Microinjection of Glu into the AV3V induced a significant depressor response without altering heart rate.
  • Procaine, atriopeptin III antiserum, and methyl atropine significantly attenuated the AV3V-induced depressor response.
  • Phentolamine and propranolol did not significantly affect the hypotensive response.

Conclusions:

  • Atriopeptin within the nucleus paraventricularis (NPV) mediates the AV3V depressor response.
  • Excitation of the cardiac vagus nerve is involved in the AV3V-induced depressor response.