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[Total intravenous anesthesia in general surgery]

M C Benito1, L M González-Zarco, J Navia

  • 1Servicio de Anestesiología-Reanimación, Hospital General Gregorio Marañón, Madrid.

Revista Espanola De Anestesiologia Y Reanimacion
|September 1, 1994
PubMed
Summary

Intravenous total anesthesia (IVTA) using propofol and fentanyl offers good hemodynamic stability and recovery in general surgery. However, reduced propofol doses in older patients or longer procedures negatively impact recovery quality.

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Area of Science:

  • Anesthesiology
  • Pharmacology
  • Surgical Care

Background:

  • Intravenous total anesthesia (IVTA) is widely used in general surgery.
  • Propofol, fentanyl, and atracurium are common agents in IVTA.
  • Evaluating side effects, recovery, and quality of IVTA is crucial for patient safety.

Purpose of the Study:

  • To assess adverse effects on hemodynamic parameters during IVTA.
  • To evaluate postanesthetic recovery and quality of IVTA.
  • To analyze the relationship between propofol dosage and patient factors.

Main Methods:

  • Prospective study of 292 general surgery patients.
  • Anesthesia administered using propofol, fentanyl, and atracurium.
  • Hemodynamic parameters, recovery time, and patient-reported outcomes were monitored.

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Main Results:

  • Hemodynamic instability observed at induction (16% systolic, 10% diastolic BP decrease).
  • 100% surgical amnesia achieved; recovery time averaged 5.95 minutes.
  • Propofol dose correlated negatively with age and anesthesia duration (p < 0.05).

Conclusions:

  • IVTA with propofol and fentanyl provides adequate anesthesia and recovery with good hemodynamic stability.
  • Reduced propofol dosage in older patients or longer surgeries negatively affects recovery.
  • Total propofol dose did not significantly correlate with recovery time or quality.