Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Pathogenesis of infectious endocarditis]

P Eggimann1, P Francioli

  • 1Département de médecine interne, Centre hospitalier universitaire vaudois, Lausanne.

Praxis
|November 22, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Validation and clinical application of a multiplex high performance liquid chromatography - Tandem mass spectrometry assay for the monitoring of plasma concentrations of 12 antibiotics in patients with severe bacterial infections" [J. Chromatogr. B 1157 (2020) 122160].

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2022
Same author

Validation and clinical application of a multiplex high performance liquid chromatography - tandem mass spectrometry assay for the monitoring of plasma concentrations of 12 antibiotics in patients with severe bacterial infections.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2020
Same author

ESCMID-EUCIC clinical guidelines on decolonization of multidrug-resistant Gram-negative bacteria carriers.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2019
Same author

Reply to Sorooshian and Snow, "Is Alternate-Day Therapeutic Drug Monitoring in the Intensive Care Unit Not Intensive Enough?"

Antimicrobial agents and chemotherapy·2018
Same author

Impact of Real-Time Therapeutic Drug Monitoring on the Prescription of Antibiotics in Burn Patients Requiring Admission to the Intensive Care Unit.

Antimicrobial agents and chemotherapy·2017
Same author

Staphylococcus aureus carriage at admission predicts early-onset pneumonia after burn trauma.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2016

Infective endocarditis pathogenesis involves predisposing heart conditions and bacteremia leading to infected vegetations. Microorganism adherence to heart valves is key to developing this serious infection.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pathophysiology

Context:

  • Infective endocarditis (IE) is a complex infection affecting heart valves.
  • Understanding IE pathogenesis is crucial for diagnosis and treatment.
  • Risk factors range from congenital heart defects to degenerative valvular disease.

Purpose:

  • To review the fundamental principles of infective endocarditis pathogenesis.
  • To elucidate the roles of predisposing factors and microbial interactions.
  • To connect the pathogenesis of vegetations to clinical manifestations.

Summary:

  • Infective endocarditis pathogenesis is initiated by predisposing cardiac conditions (rheumatic, congenital, degenerative valvulopathy) and extracardial factors.
  • These abnormalities facilitate nonbacterial thrombotic vegetation formation, which can become infected during bacteremia.

Related Experiment Videos

  • Microbial adherence to valvular tissue is a critical step in developing IE, explaining diverse clinical presentations.

    • Impact:

    • Provides a foundational understanding of infective endocarditis development.
    • Highlights the multifactorial nature of IE, involving host susceptibility and microbial virulence.
    • Informs clinical approaches to managing and preventing infective endocarditis.