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Chorea due to hyperthyroidism in old age. A case report

C Lucantoni1, S Grottoli, A Moretti

  • 1Department of Geriatry, I.N.R.C.A., (Institute National Research Centers on Aging), Ancona.

Acta Neurologica
|June 1, 1994
PubMed
Summary

Thyrotoxicosis, a condition of excess thyroid hormones, can cause chorea, an involuntary movement disorder. This study demonstrates that chorea associated with hyperthyroidism is reversible with treatment.

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Area of Science:

  • Neurology
  • Endocrinology
  • Internal Medicine

Background:

  • Hyperthyroidism, characterized by elevated thyroid hormones (T3 and T4), can manifest with various neurological symptoms.
  • Chorea is a hyperkinetic movement disorder involving involuntary, irregular, and unpredictable movements.

Observation:

  • An elderly female patient presented with thyrotoxicosis and chorea.
  • Serum T3 and T4 levels were significantly elevated, indicating hyperthyroidism.

Findings:

  • The patient's chorea resolved upon achieving euthyroidism (normal thyroid hormone levels).
  • Chorea recurred with subsequent increases in T3 and T4, confirming a direct link to hyperthyroidism.
  • The study clearly demonstrates the reversibility of chorea in the context of hyperthyroidism.

Implications:

  • Chorea should be recognized as a potential clinical manifestation of hyperthyroidism.
  • Effective management of hyperthyroidism may lead to the resolution of associated chorea.
  • This case highlights the importance of considering endocrine disorders in the differential diagnosis of movement disorders.

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