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Related Experiment Videos

Fluoxetine induced dyskinesia

A Mander1, M McCausland, B Workman

  • 1Caulfield General Medical Centre.

The Australian and New Zealand Journal of Psychiatry
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Fluoxetine can rapidly induce dyskinesia, a movement disorder, in elderly patients, even those with prior antipsychotic exposure. Symptoms resolve quickly after discontinuing fluoxetine.

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Area of Science:

  • Neuroscience
  • Pharmacology
  • Geriatrics

Background:

  • Elderly patients are susceptible to movement disorders.
  • Previous low-dose haloperidol use may influence drug-induced movement disorders.

Observation:

  • A case of fluoxetine-induced dyskinesia in an elderly woman is presented.
  • The patient had a history of low-dose haloperidol use.

Findings:

  • Fluoxetine induced dyskinesia with rapid onset and resolution.
  • This contrasts with the slower onset and persistence of neuroleptic-induced tardive dyskinesia.

Implications:

  • Fluoxetine may cause extrapyramidal syndromes in susceptible individuals.
  • Understanding these mechanisms is crucial for safe antidepressant prescribing in the elderly.