Related Experiment Videos
[Signal transmission modalities induced by growth factors: from membrane to nucleus]
1INSERM Unité 244-CEA-DBMS/BRCE, CENG-17, Grenoble.
Contraception, Fertilite, Sexualite (1992)
|September 1, 1994
Abstract:
Growth factors transduce their biological signals through transmembrane receptors that possess an intrinsic or an associated protein-tyrosine kinase activity. Two complete signalling pathways, from membrane to nucleus, were elucidated in 1993. They are described in detail in this review.
Insights
This review details two key cell signaling pathways elucidated in 1993. These pathways explain how growth factors transmit biological signals from the cell surface to the nucleus via protein-tyrosine kinases.
Area of Science:
- Cellular Biology
- Molecular Biology
- Biochemistry