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Injection granulomas. Intramuscle or intrafat?

N Haramati1, R Lorans, M Lutwin

  • 1Department of Radiology, Albert Einstein College of Medicine, Bronx, NY.

Archives of Family Medicine
|February 1, 1994
PubMed
Summary
This summary is machine-generated.

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Buttock subcutaneous fat is often thicker than standard needles used for intramuscular injections. This suggests current injection techniques may be suboptimal, especially for female patients, and longer needles might be needed.

Area of Science:

  • Anatomy
  • Radiology
  • Pharmacology

Background:

  • Intramuscular injection is a common parenteral drug administration route.
  • Anatomical variations in subcutaneous fat thickness can impact injection efficacy.
  • Calcified granulomas can serve as indicators of prior injection sites.

Purpose of the Study:

  • To assess subcutaneous fat thickness in the buttock.
  • To determine the location and depth of calcified granulomas.
  • To evaluate the adequacy of standard needle lengths for buttock intramuscular injections.

Main Methods:

  • Analysis of 338 pelvic computed tomographic scans.
  • Measurement of subcutaneous fat thickness at the upper outer quadrant of the buttock.
  • Recording the location and depth of calcified granulomas.

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Main Results:

  • 164 calcified granulomas were identified in 67 patients, with 152 in fat and 12 in muscle (P < .001).
  • Mean subcutaneous fat thickness was 5.0 +/- 1.9 cm, significantly greater in females (5.7 +/- 1.8 cm) than males (4.4 +/- 1.7 cm).
  • Subcutaneous fat thickness frequently exceeded the length of commonly used needles (3.8 cm).

Conclusions:

  • Buttock subcutaneous fat thickness often surpasses standard needle length for intramuscular injections.
  • The high prevalence of granulomas in subcutaneous fat suggests frequent suboptimal needle placement.
  • Longer needles are recommended for adult buttock intramuscular injections to ensure accurate muscle delivery.