Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Characterizing organic mood syndrome, manic type

J R Cornelius1, H Fabrega, J Mezzich

  • 1Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, PA 15213.

Comprehensive Psychiatry
|September 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anatomical and fMRI-network comparison of multiple DLPFC targeting strategies for repetitive transcranial magnetic stimulation treatment of depression.

Brain stimulation·2021
Same author

Targeting location relates to treatment response in active but not sham rTMS stimulation.

Brain stimulation·2021
Same author

A Review of the Literature of Mirtazapine in Co-Occurring Depression and an Alcohol Use Disorder.

Journal of addictive behaviors, therapy & rehabilitation·2017
Same author

Obesity, but not metabolic syndrome, negatively affects outcome in bipolar disorder.

Acta psychiatrica Scandinavica·2015
Same author

The function of medical-care systems: a logical analysis.

Perspectives in biology and medicine·2015
Same author

Language, culture and the neurobiology of pain: a theoretical exploration.

Behavioural neurology·2014
Same journal

Stroop task data does not improve prediction of CBT partial hospital treatment outcomes beyond routine clinical data: An elastic net analysis.

Comprehensive psychiatry·2026
Same journal

Probable obsessive-compulsive disorder among youth in Singapore: Prevalence, sociodemographic correlates, and the association with psychological distress, harmful alcohol use and functional impairment.

Comprehensive psychiatry·2026
Same journal

Neuroimaging insights on sleep disturbances and risk for major depressive disorder in youth: A systematic review.

Comprehensive psychiatry·2026
Same journal

Intolerance of uncertainty and symptom-level associations between generalized anxiety and depression in adolescence: A large-scale subgroup network analysis.

Comprehensive psychiatry·2026
Same journal

Default mode network hub disruption links problematic use of the Internet to brain network disorganization.

Comprehensive psychiatry·2026
Same journal

Comorbidity patterns and immune-metabolic differences in patients with acute depressive episodes.

Comprehensive psychiatry·2026
See all related articles

Organic mood syndrome, manic type (OMS-M) presents with less severe acute symptoms but greater long-term impairment than bipolar disorder. OMS-M patients show earlier onset, more developmental issues, and a high prevalence of neurological and seizure disorders.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Organic mood syndrome, manic type (OMS-M) is poorly understood.
  • Distinguishing OMS-M from functional mania (bipolar disorder, manic type [BD-M]) is clinically important.

Purpose of the Study:

  • To provide the first empirical description of OMS-M clinical features.
  • To compare OMS-M with BD-M.

Main Methods:

  • Analysis of 12 OMS-M cases diagnosed over a 5-year period.
  • Use of the DSM-III compatible Initial Evaluation Form.
  • Comparison of OMS-M with BD-M on symptom profiles and clinical factors.

Main Results:

  • OMS-M patients showed less severe acute symptoms but more long-term functional impairment than BD-M patients.

Related Experiment Videos

  • OMS-M patients had an earlier age of onset, more perinatal problems, and developmental delays.
  • Neurological disorders, particularly seizure disorders, were highly prevalent in OMS-M, exceeding other organic brain syndromes (OBS).

    • Conclusions:

    • OMS-M has distinct clinical features differentiating it from BD-M.
    • Neurological comorbidities, especially seizures, are a hallmark of OMS-M.
    • Further research is needed to understand the pathophysiology and treatment of OMS-M.