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[Uro-oxalic renal lithiasis. Special aspects]

J Thomas1, D Fompeydie, E Thomas

  • 1Service d'Urologie, Hôpital St-Antoine, Paris.

Journal D'Urologie
|January 1, 1994
PubMed
Summary

Uro-oxalic stones are more common in individuals with blood group O and tend to form on the left side. These stones are also more resistant to extracorporeal shock wave lithotripsy than other types.

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Area of Science:

  • Urology
  • Nephrology
  • Biochemistry

Background:

  • Previous research indicated a higher prevalence of uro-oxalic stones in blood group O individuals.
  • Studies suggested a predilection for uro-oxalic stones to form on the left side of the body.

Purpose of the Study:

  • To confirm the association between blood group O and uro-oxalic stones.
  • To investigate the laterality of uro-oxalic stone formation.
  • To evaluate the efficacy of extracorporeal shock wave lithotripsy (ESWL) for uro-oxalic stones.

Main Methods:

  • Retrospective analysis of patient data regarding blood type and stone location.
  • Assessment of stone resistance to ESWL using the Dornier HM3 device.
  • Analysis of stone composition, focusing on calcium oxalate monohydrate.

Main Results:

  • The study confirmed a 3:1 ratio of uro-oxalic lithiasis in blood group O versus group A individuals.
  • Uro-oxalic stones were predominantly found on the left side (39 cases) compared to the right (16 cases).
  • Uro-oxalic stones demonstrated significant resistance to ESWL, requiring a mean of 3,865 shock waves, considerably more than the general average of 2,000-2,500.

Conclusions:

  • Blood group O is associated with an increased risk of uro-oxalic stone formation.
  • Uro-oxalic stones exhibit a preference for left-sided occurrence.
  • The high resistance of uro-oxalic stones to ESWL necessitates more intensive treatment protocols.

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