[Oral immunization of human adult volunteers using a trivalent coli-vaccine]

Oral vaccination of 19 human adult volunteers with a killed trivalent E. coli vaccine induced an antibody response detectable either in sera and feces. Production of specific IgA immunoglobulins in the intestine was also observed. Antibody titres reached the highest levels 5-10 days after vaccination and were still detectable in the majority of volunteers about 2 months later.