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Neonatal depression after a protamine sulfate injection. A case report

F M Wittmaack1, F R Greer, J FitzSimmons

  • 1Department of Obstetrics and Gynecology, University of Wisconsin, Madison.

The intravenous administration of protamine sulfate in adults has been associated with acute hypotension, bradycardia and anaphylactoid reactions. However, no reports of its use in pregnancy have been available before. We describe a case of severe neonatal depression following maternal protamine sulfate injection immediately prior to delivery.

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