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Neonatal depression after a protamine sulfate injection. A case report
F M Wittmaack1, F R Greer, J FitzSimmons
1Department of Obstetrics and Gynecology, University of Wisconsin, Madison.
The Journal of Reproductive Medicine
|August 1, 1994
Summary
Maternal protamine sulfate injection before delivery may cause severe neonatal depression. This case report highlights potential risks of protamine sulfate during pregnancy.
Area of Science:
- Anesthesiology
- Neonatal Medicine
- Pharmacology
Background:
- Protamine sulfate is used to reverse heparin's anticoagulant effects.
- Known adverse effects in adults include hypotension, bradycardia, and anaphylaxis.
- Limited data exists on its use during pregnancy.