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Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation. Human Fetal
D W Branch1, L Ducat, A Fantel
1Department of Obstetrics and Gynecology, University of Utah, Salt Lake City.
Objective:
To assess the potential availability and utility of fetal tissues obtained from spontaneous abortions and from ectopic pregnancies for human transplantation therapy.
Design:
Tissue collection and analysis by personnel skilled in tissue banking.
Setting:
Procurement programs in five tissue banks located in diverse geographical areas that are funded by the National Institutes of Health.
Patients:
All women entering obstetric clinics during 1993 who consented to participate in the study.
Interventions:
None.
Main Outcome Measures:
Evaluation of the products of conception by standard developmental, histological, microbiological, and cytogenetic criteria.
Results:
From 22,235 obstetric admissions, 1250 spontaneously aborted embryos and 247 products of ectopic pregnancies were obtained. Of these, seven embryos (0.5%) were potentially useful for human transplantation therapy.
Conclusion:
Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.