Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Castleman's disease: description and comments on 3 cases]

R Arranz1, C Montesinos, M López Botet

  • 1Servicios de Hematología, Hospital de la Princesa, Madrid.

Medicina Clinica
|November 12, 1994
PubMed
Summary

Castleman disease presents heterogeneously. Localized forms (HV) are surgically treated, while symptomatic multicentric forms (PC) respond well to chemotherapy or steroids.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First-trimester cavum veli interpositi: prevalence and natural history.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2023
Same author

Allogeneic hematopoietic stem cell transplantation for advanced mycosis fungoides and Sézary syndrome. An updated experience of the Lymphoma Working Party of the European Society for Blood and Marrow Transplantation.

Bone marrow transplantation·2021
Same author

A simple method for SARS-CoV-2 detection by rRT-PCR without the use of a commercial RNA extraction kit.

Journal of virological methods·2020
Same author

Immune-related adverse events predict the therapeutic efficacy of anti-PD-1 antibodies in cancer patients.

European journal of cancer (Oxford, England : 1990)·2019
Same author

Image processing and machine learning in the morphological analysis of blood cells.

International journal of laboratory hematology·2018
Same author

Autologous stem cell transplantation (ASCT) in patients with mantle cell lymphoma: a retrospective study of the Spanish lymphoma group (GELTAMO).

Annals of hematology·2017

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Castleman disease is a rare lymphoproliferative disorder with diverse clinical and histological presentations.
  • Understanding its heterogeneity is crucial for accurate diagnosis and effective treatment strategies.

Observation:

  • Presents three distinct cases of Castleman disease: one localized hyaline-vascular (HV) form and two multicentric plasmocellular (PC) forms.
  • The HV case was asymptomatic and treated with surgical resection.
  • The PC cases exhibited varied clinical symptoms, with one responding to polychemotherapy and the other to steroids.

Findings:

  • Demonstrates the clinical heterogeneity of Castleman disease, ranging from localized to multicentric forms.
  • Highlights successful therapeutic outcomes with different modalities based on disease subtype and presentation.
  • Underscores the challenges in defining Castleman disease as a singular entity due to its varied nature.

Implications:

  • Emphasizes the need for individualized treatment approaches in Castleman disease management.
  • Suggests further research into the pathogenesis and classification of Castleman disease subtypes.
  • Informs clinical practice regarding the diagnosis and management of this complex disorder.

Related Experiment Videos