[Activity of neutrophilic granulocytes and hematologic picture in rabbits immunized with chlamydia psittaci]

The study was aimed at investigation of selected elements of nonspecific immunity (spontaneous and stimulated NBT reduction test and myeloperoxidase activity of neutrophilic granulocytes) and specific serological response in rabbits immunized twice with suspension of cells of C. psittaci inactivated by formaldehyde. Specific antibodies were detected by complement fixation test and in a titer of 16 or higher were found between 42 and 56 day of the experiment. Statistically significant decrease of myeloperoxidase activity of granulocytes was observed between 14 and 21 day of the experiment, while diminishing values of results of spontaneous NBT reduction test was seen mainly between 35 and 56 day of experiment. The authors conclude that obtained results suggest occurrence of periodical decrease of nonspecific immunity may occur after immunization of animals with inactivated C. psittaci suspension.