[Peroxide radicals in the metabolism of toxic substances]

The free radicals resulting from the metabolism of oxygen and some xenobiotics, can induce, when a limit concentration is exceeded, toxic effects due to their action on DNA, enzymes and fatty acids. Therefore, the association of oxygen therapy with drug administration may have a more or less beneficial effect. Thus, in a long-term treatment with drugs which by metabolized release free radicals, the use of exogenous compounds for protecting the human body need to be administered.