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Fructosamine cannot replace HbA1c in the management of type 2 diabetes (NIDDM)
K Furuseth1, D Bruusgaard, O Rutle
1Department of community medicine and general practice, University of Oslo, Norway.
Objective:
To compare HbA1c, fructosamine, and blood glucose and discuss to what degree Hba1c can be replaced by fructosamine.
Design:
Cross-sectional study.
Patients:
87 unselected patients coming for 112 consecutive consultations.
Main Outcome Measures:
Fructosamine, HbA1c, blood glucose.
Results:
The following Pearson correlation coefficients were found: Blood glucose/fructosamine 0.45, HbA1c/blood glucose 0.64, and HbA1c/fructosamine 0.39. Sensitivity and specificity of fructosamine and blood glucose to detect HbA1c > or = 8.0% was shown.
Conclusion:
Our study indicates that fructosamine and fasting capillary blood glucose are poor indicators of the level of HbA1c in NIDDM patients.