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Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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Calcium threshold in human plasma clotting kinetics

F I Ataullakhanov1, A V Pohilko, E I Sinauridze

  • 1National Scientific Center for Hematology, Russian Academy of Medical Sciences, Moscow.

Thrombosis Research
|August 15, 1994
PubMed
Summary

This study reveals a critical threshold for calcium ion concentration in human blood plasma coagulation. Below 0.25 mM, thrombin generation is minimal, indicating a switch-like activation of blood clotting.

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