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Related Experiment Videos

Mechanical thrombectomy with the Amplatz device: human experience

S M Tadavarthy1, P D Murray, S Inampudi

  • 1Minneapolis Heart Institute, Abbott Northwestern Hospital, MN 55407.

Journal of Vascular and Interventional Radiology : JVIR
|September 1, 1994
PubMed
Summary

The Amplatz thrombectomy device offers a rapid and effective method for mechanical clot removal in arteries and grafts. Early results show promise, particularly for synthetic bypass grafts, with potential for wider application.

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Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Medical Devices

Background:

  • Thrombosis in arterial and synthetic bypass grafts poses significant clinical challenges.
  • Effective and rapid thrombus removal is crucial for restoring blood flow and limb salvage.

Purpose of the Study:

  • To evaluate the early clinical experience with the Amplatz thrombectomy device for mechanical arterial and graft thrombectomy.
  • To assess the safety and efficacy of this novel thrombectomy technique.

Main Methods:

  • Preliminary data from 14 patients treated with the Amplatz thrombectomy catheter were analyzed.
  • The device was used in arterial polytetrafluoroethylene grafts, native arteries, and for venous thrombosis.

Main Results:

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  • Complete clot removal was achieved in 11 patients, with partial removal in three.
  • Mean thrombectomy time was 2 minutes 45 seconds, with minimal distal embolization.
  • Mechanical clot dissolution consistently caused hemolysis without adverse clinical effects.

Conclusions:

  • Mechanical thrombectomy using the Amplatz device is a new, effective, and rapid technique for thrombus removal.
  • The device shows particular promise for occluded synthetic femoral-to-popliteal bypass grafts.
  • Steerability and contralateral approach capability could enhance the device's broader applicability.