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Updated: Aug 8, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
Some biochemical and pharmacological aspects of free radical-mediated tissue damage
1K. Marcinkowski Medical Academy, Poznań, Poland.
Abstract:
Living in aerobic conditions carries a risk of oxidative stress, in connection with free radical deleterious action on tissues and cells. Free radical mechanisms have been implicated in the pathogenesis of many diseases, as well as in host defense against various invading microorganisms. A substantial body of evidence has been reported on free radical involvement in inflammation, ischaemia/reperfusion injury, atherosclerosis and many other pathologies. The aim of this paper is to review selected literature and opinions concerning free radical-induced damage to tissues and to present xenobiotic contribution to oxidative stress.
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