[Method of the assessment of neutrophilic leukocyte and monocyte interactions in a mixed cell culture]

The author offers a test system for studies of the interactions of agglutinating polymorphonuclear cells and neutrophilic leukocytes of human blood in a mixed cell culture. This method has demonstrated a modulation of the structural and functional status of the interacting cells. The counts of polymorphonuclear cells, expressing HLA-DR antigens, and of neutrophilic leukocytes with receptors to Fc fragment of IgG grow in the course of cell cultivation, and a number of cytokines, interleukin-1 and factors of chemotaxis of polymorphonuclear cells and neutrophilic leukocytes, are produced.