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Related Experiment Videos

Non-Hodgkin's lymphoma

T C Greiner1, L J Medeiros, E S Jaffe

  • 1Hematopathology Section, Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland 20892.

Cancer
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

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Non-Hodgkin's lymphoma (NHL) incidence rose 50% from 1973-1988, with changes in classification impacting data analysis. Advances in pathology may necessitate future SEER data modifications for accurate epidemiologic trends.

Area of Science:

  • Oncology
  • Epidemiology
  • Pathology

Background:

  • Non-Hodgkin's lymphoma (NHL) understanding has advanced significantly.
  • Terminology and classification changes may impact Surveillance, Epidemiology, and End Results (SEER) data analysis.

Purpose of the Study:

  • To review NHL incidence rates across different subgroups.
  • To analyze SEER data from 1973 to 1987.

Main Methods:

  • Reviewed SEER data for NHL subgroups.
  • Analyzed data across three distinct time periods: 1973-1977, 1978-1982, and 1983-1987.

Main Results:

  • NHL incidence increased by 50% between 1973 and 1988.
  • Diffuse large cell lymphoma is the most common type (nearly 30%).

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  • Increased rates in certain NHL subtypes linked to the AIDS epidemic; environmental factors identified as potential risks.

    • Conclusions:

    • Pathologists' enhanced ability to define new entities necessitates future SEER data collection modifications.
    • Updating data collection will address Working Formulation limitations and improve epidemiologic trend evaluation.