Related Experiment Video
Updated: Aug 5, 2026
A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model
Published on: October 14, 2016
Cutaneous involvement in chronic myelomonocytic leukemia
D M O'Connell1, W A Fagan, S M Skinner
1Department of Dermatology, University of Texas Health Science Center, San Antonio 78284-7876.
Background:
Chronic myelomonocytic leukemia has been associated with various nonspecific cutaneous manifestations. Rarely has the leukemia been reported to directly affect the skin.
Methods:
This case documents the progression of a patient who ultimately developed chronic myelomonocytic leukemia, by clinical examination, hematologic parameters, dermatopathology, and bone marrow pathology.
Results:
The skin showed nonspecific cutaneous involvement, progressing to specific leukemic lesions parallel with increasing systemic and hematologic involvement.
Conclusions:
Chronic myelomonocytic leukemia can manifest with lesions of leukemia cutis. The possibility of nonspecific cutaneous involvement in the preleukemic phase exists.
