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Studies on the structure of T lymphocyte receptors using xenogeneic anti-idiotype antibodies
The present study is an attempt to produce xenogeneic anti-idiotype antibodies (Id) against mouse anti-H2 antibodies. The purpose is to obtain such anti-Id antibodies with reactivity against both B and T cells in quantities which will allow thorough investigation of the biochemical nature of the T cell receptor for alloantigen. Data are presented from experiments performed with an antiserum 5936 which was obtained after immunization with C57B1/6 anti-CBA antibodies.
The present study is an attempt to produce xenogeneic anti-idiotype antibodies (Id) against mouse anti-H2 antibodies. The purpose is to obtain such anti-Id antibodies with reactivity against both B and T cells in quantities which will allow thorough investigation of the biochemical nature of the T cell receptor for alloantigen. Data are presented from experiments performed with an antiserum 5936 which was obtained after immunization with C57B1/6 anti-CBA antibodies.