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Effect of a low molecular weight peptide bound to liver mitochondrial DNA on in vitro DNA duplication
Bollettino Della Societa Italiana Di Biologia Sperimentale
|December 1, 1993
Abstract:
Authors tested "in vitro" action of a low molecular weight peptide fraction extracted by mitochondrial DNA from calf liver. The fraction acts upon duplication performed by E. Coli DNA polymerase I on poli dAT dAT template inhibiting chain elongation. The authors hypothesize that a similar role is exerted by this fraction "in vitro" on mitochondrial DNA template.