Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Deficient cerebral activation pattern in stroke recovery

B Weder1, R J Seitz

  • 1Department of Neurology, Kantonsspital, St Gallen, Switzerland.

Neuroreport
|January 12, 1994
PubMed
Summary

Stroke survivors show reduced brain activation during tactile discrimination tasks compared to healthy individuals. This suggests motor recovery does not fully restore sensory processing in the brain after hemiplegic stroke.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

What influence do face masks have on reading emotions in faces?

Neuroimage. Reports·2025
Same author

The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis.

Journal of Crohn's & colitis·2019
Same author

Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis.

Scientific reports·2018
Same author

BCL-2 levels do not predict azathioprine treatment response in inflammatory bowel disease, but inhibition induces lymphocyte apoptosis and ameliorates colitis in mice.

Clinical and experimental immunology·2018
Same author

Myeloid differentiation primary response gene (MyD) 88 signalling is not essential for intestinal fibrosis development.

Scientific reports·2017
Same author

Neuroanatomical correlates of tube dependency and impaired oral intake after hemispheric stroke.

European journal of neurology·2016

Area of Science:

  • Neuroscience
  • Cognitive Neurology
  • Neuroimaging

Background:

  • Hemiplegic stroke survivors often exhibit motor deficits.
  • Assessing residual sensory function and associated neural correlates is crucial for understanding recovery.
  • Tactile discrimination is a complex sensory function that relies on specific brain networks.

Purpose of the Study:

  • To investigate cerebral blood flow patterns during tactile discrimination in patients recovered from hemiplegic stroke.
  • To compare brain activation in stroke survivors versus healthy volunteers during a sensory task.
  • To correlate neuroimaging findings with clinical observations of motor and sensory function.

Main Methods:

  • Positron emission tomography (PET) scans measuring regional cerebral blood flow (rCBF).

Related Experiment Videos

  • Unilateral tactile discrimination of macrogeometric objects as the experimental task.
  • Comparison of brain activation between a group of recovered hemiplegic stroke patients and healthy control subjects.

    • Main Results:

    • Healthy volunteers showed regular activation in primary sensorimotor cortex, supplementary motor area, superior parietal lobule, and premotor cortex.
    • Stroke patients exhibited consistent activation only in the primary sensorimotor cortex.
    • Parietal association, premotor, and midfrontal cortical areas were less consistently activated in patients compared to controls.

    Conclusions:

    • Patients recovered from hemiplegic stroke demonstrate altered patterns of cerebral activation during tactile discrimination.
    • Reduced activation in higher-order sensory areas correlates with persistent deficits in tactile discrimination, despite motor recovery.
    • Neuroimaging highlights specific neural network differences underlying sensory processing deficits post-stroke.