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Cross-linking of iodinated prolactin to rat liver nuclear protein
J Knopp1, Y Zaliberová, J Jurcovicová
1Intitute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava.
Endocrine Regulations
|March 1, 1993
Abstract:
The specific binding of prolactin (PRL) in rat liver nuclei have been examined. Following cross-linking with the use of 125I-rat prolactin and autoradiography the evidence is presented for the specific binding of PRL to a nuclear protein with low Mr of about 7000. This study shows that the PRL binder in rat liver nuclei is a small protein and probably differs from molecular form of the rat liver membrane prolactin receptor.