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Related Experiment Videos

B-cell malignancy after low grade T-cell lymphoma

A Klein1, Y Manor, S Abed

  • 1Department of Life Sciences, Sapir Medical Centre, Bar-Ilan University, Ramat-Gan, Israel.

Cancer
|July 1, 1994
PubMed
Summary

This study identified two distinct lymphoproliferative diseases in a patient initially diagnosed with non-Hodgkin's lymphoma. Analysis revealed a monoclonal T-cell population in a lymph node and a monoclonal B-cell population in peripheral blood.

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Area of Science:

  • Hematology
  • Immunology
  • Oncology

Background:

  • A 38-year-old woman was diagnosed with low-grade, small lymphocytic, non-Hodgkin's lymphoma.
  • Thirty months post-diagnosis, abnormal lymphoid cells appeared in peripheral blood (PB).
  • Analysis of lymph node (LN) and PB samples was conducted to investigate these findings.